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Home » Products » Anti-Cancer Products » Ambrisentan

Ambrisentan

Ambrisentan
Ambrisentan
Product Code : #0066
Brand Name : Endobloc 5
Product Specifications
  • Minimum Order Quantity
  • Formulations Type
  • Chemical Drug
  • Formulations Form
  • Tablets
  • Gender/Age Group
  • Adult
Trade Information
  • Payment Terms
  • Cash on Delivery (COD), Cash Advance (CA), Delivery Point (DP), Western Union
  • Main Export Market(s)
  • Asia, Australia, South America, Eastern Europe, Africa
  • Main Domestic Market
  • All India
Product Description

Ambrisentan (U.S. trade name Letairis; E.U. trade name Volibris; India trade name Pulmonext by MSN labs) is a drug indicated for use in the treatment of pulmonary hypertension.

The peptide endothelin constricts muscles in blood vessels, increasing blood pressure. Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA).[1] Ambrisentan significantly improved exercise capacity (6-minute walk distance) compared with placebo in two double-blind, multicenter trials (ARIES-1 and ARIES-2).[2]

Ambrisentan was approved by the U.S. Food and Drug Administration (FDA) and European Medicines Agency, and designated an orphan drug, for the treatment of pulmonary hypertension.[3][4][5][6][7]


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