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Itraconazole

Itraconazole
Itraconazole
Product Code : JH/00046
Brand Name : ITRAJOHN-100
Product Specifications
  • Formulations Type
  • Chemical Drug
  • Formulations Form
  • Tablets
  • Gender/Age Group
  • Adult
Product Description

Itraconazole-100Mg  Tablet   
Itraconazole (code name R51211), invented in 1984, is a triazoleantifungal agent prescribed to patients with fungal infections. The drug may be given orally or intravenously.

Medical uses[edit]

Itraconazole has a broader spectrum of activity than fluconazole (but not as broad as voriconazole or posaconazole). In particular, it is active against Aspergillus, which fluconazole is not. It is also licensed for use in blastomycosis, sporotrichosis, histoplasmosis, and onychomycosis. Itraconazole is over 99% protein-bound and has virtually no penetration into cerebrospinal fluid. Therefore, it should never be used to treat meningitis or other central nervous system infections.[3] According to the Johns Hopkins Abx Guide, it has "negligible CSF penetration, however treatment has been successful for cryptococcal and coccidioidal meningitis".[4]

It is also prescribed for systemic infections, such as aspergillosis, candidiasis, and cryptococcosis, where other antifungal drugs are inappropriate or ineffective.

 

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